Acute ataxia, Graves' disease, and stiff person syndrome
Identifieur interne : 003034 ( Main/Exploration ); précédent : 003033; suivant : 003035Acute ataxia, Graves' disease, and stiff person syndrome
Auteurs : Su-Ynn Chia [Singapour] ; Richard Chua [Singapour] ; Yew-Long Lo [Singapour] ; Meng-Cheong Wong [Singapour] ; Ling-Ling Chan [Singapour] ; Eng-King Tan [Singapour]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-10-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Antithyroid Agents (administration & dosage), Ataxia, Ataxia (diagnosis), Ataxia (immunology), Ataxia (therapy), Autoantibodies (blood), Carbimazole (administration & dosage), Combined Modality Therapy, Comorbidity, Diagnosis, Differential, Electromyography, Female, Glutamate Decarboxylase (immunology), Graves Disease (diagnosis), Graves Disease (immunology), Graves Disease (therapy), Graves disease, Graves' disease, Humans, Immunization, Passive, Immunosuppression, Middle Aged, Nervous system diseases, Neurologic Examination, Plasmapheresis, Stiff man syndrome, Stiff-Person Syndrome (diagnosis), Stiff-Person Syndrome (immunology), Stiff-Person Syndrome (therapy), Stroke (diagnosis), Thyrotoxicosis (diagnosis), Thyrotoxicosis (immunology), Thyrotoxicosis (therapy), ataxia, stiff person syndrome.
- MESH :
- chemical , administration & dosage : Antithyroid Agents, Carbimazole.
- chemical , blood : Autoantibodies.
- diagnosis : Ataxia, Graves Disease, Stiff-Person Syndrome, Stroke, Thyrotoxicosis.
- immunology : Ataxia, Glutamate Decarboxylase, Graves Disease, Stiff-Person Syndrome, Thyrotoxicosis.
- therapy : Ataxia, Graves Disease, Stiff-Person Syndrome, Thyrotoxicosis.
- Combined Modality Therapy, Comorbidity, Diagnosis, Differential, Electromyography, Female, Humans, Immunization, Passive, Immunosuppression, Middle Aged, Neurologic Examination, Plasmapheresis.
Abstract
Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21703
Affiliations:
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Le document en format XML
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Institute, Singapore General Hospital</wicri:regionArea><wicri:noRegion>Singapore General Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Wong, Meng Heong" sort="Wong, Meng Heong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name><affiliation wicri:level="1"><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Neurology, National Neuroscience Institute, Singapore General Hospital</wicri:regionArea><wicri:noRegion>Singapore General Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Chan, Ling Ing" sort="Chan, Ling Ing" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name><affiliation wicri:level="1"><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Radiology, Singapore General Hospital</wicri:regionArea><wicri:noRegion>Singapore General Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Tan, Eng Ing" sort="Tan, Eng Ing" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name><affiliation wicri:level="1"><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Neurology, National Neuroscience Institute, Singapore General Hospital</wicri:regionArea><wicri:noRegion>Singapore General Hospital</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-10-15">2007-10-15</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">13</biblScope><biblScope unit="page" from="1969">1969</biblScope><biblScope unit="page" to="1971">1971</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">3070736F0F60F59E6E6CD41354614296883642EF</idno><idno type="DOI">10.1002/mds.21703</idno><idno type="ArticleID">MDS21703</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antithyroid Agents (administration & dosage)</term><term>Ataxia</term><term>Ataxia (diagnosis)</term><term>Ataxia (immunology)</term><term>Ataxia (therapy)</term><term>Autoantibodies (blood)</term><term>Carbimazole (administration & dosage)</term><term>Combined Modality Therapy</term><term>Comorbidity</term><term>Diagnosis, Differential</term><term>Electromyography</term><term>Female</term><term>Glutamate Decarboxylase (immunology)</term><term>Graves Disease (diagnosis)</term><term>Graves Disease (immunology)</term><term>Graves Disease (therapy)</term><term>Graves disease</term><term>Graves' disease</term><term>Humans</term><term>Immunization, Passive</term><term>Immunosuppression</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Neurologic Examination</term><term>Plasmapheresis</term><term>Stiff man syndrome</term><term>Stiff-Person Syndrome (diagnosis)</term><term>Stiff-Person Syndrome (immunology)</term><term>Stiff-Person Syndrome (therapy)</term><term>Stroke (diagnosis)</term><term>Thyrotoxicosis (diagnosis)</term><term>Thyrotoxicosis (immunology)</term><term>Thyrotoxicosis (therapy)</term><term>ataxia</term><term>stiff person syndrome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antithyroid Agents</term><term>Carbimazole</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Autoantibodies</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Ataxia</term><term>Graves Disease</term><term>Stiff-Person Syndrome</term><term>Stroke</term><term>Thyrotoxicosis</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Ataxia</term><term>Glutamate Decarboxylase</term><term>Graves Disease</term><term>Stiff-Person Syndrome</term><term>Thyrotoxicosis</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Ataxia</term><term>Graves Disease</term><term>Stiff-Person Syndrome</term><term>Thyrotoxicosis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Combined Modality Therapy</term><term>Comorbidity</term><term>Diagnosis, Differential</term><term>Electromyography</term><term>Female</term><term>Humans</term><term>Immunization, Passive</term><term>Immunosuppression</term><term>Middle Aged</term><term>Neurologic Examination</term><term>Plasmapheresis</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Ataxie</term><term>Maladie de Basedow</term><term>Pathologie du système nerveux</term><term>Syndrome de l'homme raide</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Singapour</li></country></list><tree><country name="Singapour"><noRegion><name sortKey="Chia, Su Nn" sort="Chia, Su Nn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name></noRegion><name sortKey="Chan, Ling Ing" sort="Chan, Ling Ing" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name><name sortKey="Chia, Su Nn" sort="Chia, Su Nn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name><name sortKey="Chua, Richard" sort="Chua, Richard" uniqKey="Chua R" first="Richard" last="Chua">Richard Chua</name><name sortKey="Lo, Yew Ong" sort="Lo, Yew Ong" uniqKey="Lo Y" first="Yew-Long" last="Lo">Yew-Long Lo</name><name sortKey="Tan, Eng Ing" sort="Tan, Eng Ing" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name><name sortKey="Wong, Meng Heong" sort="Wong, Meng Heong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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